THE ANALGESIC EFFECT TEST OF KECOMBRANG FLOWER ETHANOL EXTRACT(Etlingera elatior .jack) ON MALE WHITE MICE (Mus musculus)
Background : Ibuprofen is a drug that is commonly used when the body experiences pain. In this study, the medicinal plant that will be tested for its analgesic effect on mice is Kecombrang flower.
Methods: Kecombrang flowers were first used as ethanol extract with two different concentrations, namely 400 mg/kgBb and 800 mg/kgBb. The experimental animals used were 20 male white mice which were divided into 4 groups where each group consisted of 5 mice. Each group of mice was given a dose treatment first, then 30 minutes after that, 1.1% acetic acid solution was given via ip, after that, pay attention to the amount of writhing shown by the mice.
Results: From the 2 concentrations of kecombrang flower ethanol extract given, it turned out that the 400 mg/kgBb dose group showed fewer stretches than the 800 mg/kgBb dose group, but the analgesic effect was still low compared to the control group + namely ibuprofen.
Key words : Kecombrang flower, analgesic and mice
Copyright (c) 2022 JKPharm Jurnal Kesehatan Farmasi
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work