THE ANALGESIC EFFECT TEST OF KECOMBRANG FLOWER ETHANOL EXTRACT(Etlingera elatior .jack) ON MALE WHITE MICE (Mus musculus)

  • Fita Selonni AKADEMI FARMASI PRAYOGA PADANG
  • Tuty Taslim
Keywords: Kecombang flowers, analgesic, mice

Abstract

Background : Ibuprofen is a drug that is commonly used when the body experiences pain. In this study, the medicinal plant that will be tested for its analgesic effect on mice is Kecombrang flower.

Methods: Kecombrang flowers were first used as ethanol extract with two different concentrations, namely 400 mg/kgBb and 800 mg/kgBb. The experimental animals used were 20 male white mice which were divided into 4 groups where each group consisted of 5 mice. Each group of mice was given a dose treatment first, then 30 minutes after that, 1.1% acetic acid solution was given via ip, after that, pay attention to the amount of writhing shown by the mice.

Results: From the 2 concentrations of kecombrang flower ethanol extract given, it turned out that the 400 mg/kgBb dose group showed fewer stretches than the 800 mg/kgBb dose group, but the analgesic effect was still low compared to the control group + namely ibuprofen.

Key words : Kecombrang flower, analgesic and mice

Published
2022-12-29
How to Cite
1.
Selonni F, Taslim T. THE ANALGESIC EFFECT TEST OF KECOMBRANG FLOWER ETHANOL EXTRACT(Etlingera elatior .jack) ON MALE WHITE MICE (Mus musculus). JPharm [Internet]. 29Dec.2022 [cited 9Feb.2023];4(2):25 -30. Available from: https://jurnal.poltekkespalembang.ac.id/index.php/Jkpharm/article/view/1428