KADAR ZINC DAN KADAR IGF-1 SERUM PADA ANAK SEKOLAH DASAR DI KECAMATAN TUAH NEGERI KABUPATEN MUSIRAWAS
KADAR ZINC SERUM DAN IGF-1 SERUM
Abstract
Latar belakang: Zinc merupakan salah satu mikronutrien penting yang dibutuhkan oleh tubuh. Rendahnya zinc dalam tubuh akan menghambat efek metabolit hormon pertumbuhan atau GH, sehingga sintesis dan sekresi Insulin Like Growth Factor 1 (IGF-1) berkurang dan berdampak terhadap reterdasi pertumbuhan. Penelitian ini bertujuan untuk menganalisis hubungan antara kadar zinc serum dan kadar IGF-1 serum pada anak Sekolah Dasar di Kecamatan Tuah Negeri Kabupaten Musi Rawas.
Metode: Desain penelitian ini adalah cross sectional, dengan sampel anak Sekolah Dasar usia 7-13 tahun. Sampel berjumlah 79 orang yang diambil secara random. Dilakukan pengukuran status gizi berdasarkan TB/U dan pengambilan darah untuk pengukuran kadar Zn dan IGF-1 serum. Adapun data karakteristik sampel diperoleh melalui kuesioner, sedangkan pengukuran kadar Zn dan IGF-1 serum dilakukan dengan metode ELISA. Selanjutnya data dianalisis menggunakan uji chi-square. Hasil: berdasarkan pengukuran status gizi didapatkan 19 (24%) anak mengalami stunting dan 60 (76%) anak memiliki status gizi normal. Pada anak stunting 89.5% mempunyai kadar Zn yang rendah dan 78.9% mempunyai kadar IGF-1 yang rendah. Hasil analisis bivariat didapatkan p=0.017 dan PR=5.667 untuk hubungan antara status gizi dan kadar Zn serum; p=0.000 dan PR=8.983 untuk hubungan antara kadar Zn serum dengan kadar IGF-1 serum. terdapat hubungan yang bermakna antara status gizi dengan kadar Zn serum dan kadar Zn serum dengan IGF-1 serum.
Kesimpulan: Anak yang mengalami stunting beresiko 5.667 kali mempunyai kadar Zn yang rendah dan anak dengan kadar Zn serum yang rendah beresiko 8.983 kali mempunyai kadar IGF-1 serum yang rendah juga. Zn dan IGF-1 diperlukan dalam proses pertumbuhan anak. Perlunya edukasi kesehatan tentang pentingnya asupan zinc pada orang tua, agar kebutuhan Zn pada anak dapat terpenuhi.
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