LEVEL OF COMPLIANCE WITH THE USE OF ANTI-TUBERCULOSIS DRUGS IN ADULT PULMONARY TUBERCULOSIS PATIENTS AT THE OUTPATIENT PULMONARY POLYCLINIC OF DR. HARJONO S PONOROGO
Abstract
Background: Tuberculosis is an infectious disease that causes health disorders and is the leading cause of death worldwide. Adherence to medication is a very important indicator of the successful recovery of tuberculosis patients for 6-9 months where patients have to take medication non-stop. Non-compliance of TB patients causes low patient recovery, high mortality rate, increased recurrence, and more fatal is the occurrence of (immunity) of germ resistance to standard treatment. This study has a formulation of the problem of how the level of compliance with the use of anti-tuberculosis drugs in adult pulmonary TB patients at Dr. Harjono Ponorogo Hospital.
Methods: This research is a qualitative descriptive research with a survey method. The instrument used to collect data by providing a closed statement on a questionnaire sheet that has been tested for valdiance and reliability. The research was conducted at the Outpatient Pulmonary Poly of the Dr. Harjono Ponorogo Regional General Hospital in April 2024. The sample in this study was taken from patients who were undergoing advanced phase pulmonary TB treatment at least 4 months after treatment, were over 17 years old, and were willing to be respondents. The sample amounted to 22 respondents with a sampling technique using the purposive sampling technique. The data obtained were analyzed using univariate analysis.,
Results: Result of the study showed that good compliance amounted to 16 patients (72.7%), moderate compliance amounted to 5 patients (22.7%) and less than 1 patient (4.5%).
Conclusion: It was concluded that the compliance rate for the use of anti-tuberculosis drugs at Dr. Harjono Ponorogo Hospital had good compliance of 72.7%.
References
Afwansyah, M., & Dania, H. 2022. Tingkat Kepatuhan Penggunaan Obat Anti Tuberkulosis Paru Di Rumah Sakit PKU Muhammadiyah Bantl Menggunakan Metode Pill – Count Dan MARS. Jurnal Famasains, Vol (9) No. 1, hal 9 – 17
Ahdiyah, N. N., Andriani, M., & Andriani, L. 2022. Tingkat Kepatuhan Penggunaan Obat Anti Tuberkulosis Pada Pasien TB Paru Dewasa Di Puskesmas Putri Ayu. Lumbung Farmasi: Jurnal Ilmu Kefarmasian, Vol (3) No. 1, hal 23 – 28
Amran, R., Abdulkadir, W., & Madania, M. 2021. Tingkat Kepatuhan Penggunaan Obat Anti Tuberkulosis Pada Pasien Di Puskesmas Tombulilato Kabupaten Bone Bolango. Indonesia Journal Of Pharmaceutical Education, Vol (1) No. 1 hal 57 – 66
Aqil, A.D.C. 2020. Studi Kepustakaan Mengenai Kualitas Pelayanan Terhadap Kepuasan Pasien Rawat Jalan Di Rumah Sakit. Jurnal Ilmiah Pemenang, Vol (2) No. 2, hal 1 – 6
Arikunto, S. 2013. Prosedur Penelitian Suatu Pendekatan Praktik. Jakarta: Rineka Cipta
Dinas Kesehatan Kabupaten Ponorogo. 2023. Profil Kesehatan Kabupaten Ponorogo Tahun 2022. Ponorogo: Dinas Kesehatan Kab. Ponorogo
Direktorat Jenderal Pencegahan Dan Pengendalian Penyakit. 2023. Laporan Program Penanggunalangan Tuberkulosis Tahun 2022. Jakarta: Kementrian Kesehatan Republik Indonesi
Fauziah, E.B. 2016. Kepatuhan Penggunaan Obat Pada Pasien Yang Mendapat Terapi Antibiotik Di Puskesmas Mendawai Pangkalan Bun. Jurnal Surya Medika, Vol 2 No. 1, hal 38-46
Ganiswarna, S. 1995. Farmakologi dan Terapi edisi IV. Farmakologi Fakultas Kedokteran Universitas Indonesia, Jakarta: Gaya Baru
Global tuberculosis report. 2022. Geneva: World Health Organization; 2022. (online), (https://doi.org/10.1016/s2666-5247(22)00359-7), diakses 22 Desember 2023
Halim, M., Sabrina, A.S., & Aris, M. 2023. Kepatuhan Pasien Rawat Jalan Poli Paru Dalam Penggunaan Obat Anti Tuberkulosis (OAT) Di Rumah Sakit Kartika Husada Jatiasih Bekasi. Jurnal Farmasi IKIFA, Vol (2) No. 1, hal 30 – 37
Hardani, et al. 2017. Metode Penelitian Kualitatif & Kuantitaif. Yogyakarta: CV. Pustaka Ilmu Group
Hendra, G.A., Susanto, F.H., & Choirunniza, A.N. 2023. Implementasi Aplikasi Mobile “My TB Alaram” Sebagai Instrumen Edukasi Dalam Mengukur Kepatuhan Pasien TBC Dewasa. Jurnal Ilmu Farmasi Dan Farmasi Klinik, Vol (20) No. 2 hal 66 – 74
Kemeskes RI. 2011. Modul Penggunaaan Obat Rasional, Jakarta: Kementrian Kesehatan Republik Indonesia
Kemenkes RI. 2019. Keputusan Menteri Kesehatan Republik Indonesia Nomor HK.01.07/MENKES/90/2019 Tentang Pedoman Nasional Pelayanan Kedokteran Tata Laksana HIV. Jakarta: Kementrian Kesehatan Republik Indonesia
Kemenkes RI. 2019. Keputusan Menteri Kesehatan Republik Indonesia Nomor HK.01.07./MENKES/755/2019 Tahun 2019 Tentang Pedoman Nasional Pelayanan Kedokteran Tatalaksana Tuberkulosis. Jakarta: Kementrian Kesehatan Republik Indonesia
Kemenkes RI. 2020. Strategi Nasional Penanggulangan Tuberkulosis di Indonesia 2020-2024. Jakarta: Kementrian Kesehatan Republik Indonesia
Mar’iyah, K. dan Zulkarnain. 2021. Patofisiologi Penyakit Infeksi Tuberkulosis. Prosiding Seminar Nasional Biologi, Vol (7) No. 1, hal 88 – 92
Papeo, D. R. P., Immaculata, M., & Rukmawati, I 2021. Hubungan Antara Kepatuhan Minum Obat (MMAS-8) Dan Kualitas Hidup (WHOQOL-BREF) Penderita Tuberkulosis Di Puskesmas Di Kota Bandung. Indonesia journal of pharmaceutical education, Vol (1) No. 2 hal 86 – 9
Paramita, et al. 2021. Metode Penelitian Kuantitatif. Lumajang: Widyagama Gama Press
Pasaribu, G.F., Handini, M.C., Manurung, J., Manurung, K., Sembiring, R., & Siagian, M.T. 2023. Ketidakpatuhan Minum Obat Pada Pasien TB Paru: Studi Kualitatif. Prima Medika Sains, Vol (5) No. 1 hal 48 – 56
Permenkes RI. 2014. Peraturan Menteri Kesehatan Republik Indonesia Nomor 35 Tahun 2014 Tentang Standar Pelayanan Kefarmasian Di Apotek. Jakarta: Peraturan Mentri Kesehatan Republik Indonesia
Permenkes RI. 2016. Peraturan Menteri Kesehatan Republik Indonesia Nomor 72 Tahun 2016 Tentang Standar Pelayanan Kefarmasian Di Rumah Sakit. Jakarta: Peraturan Mentri Kesehatan Republik Indonesia
Permenkes RI. 2021. Peraturan Menteri Kesehatan RI Nomor 28 Tahun 2021 Tentang Pedoman Penggunaan Antibiotik. Jakarta: Peraturan Mentri Kesehatan Republik Indonesia
Purnomo, Rochmat Aldiy. 2016. Analisis Statistik Ekonomi Dan Bisnis Dengan SPSS. Ponorogo: CV. Wade Group
Pratama, R.A., Diniarti, F. & Handayani, T.S. 2023. Faktor – Faktor Yang Mempengaruhi Kepatuhan Minum Obat Pada Pasien TB Paru Kasus Baru Di RSUD Curup Tahun 2022. Jurnal Sain Dan Kesehatan, Vol (12) No. 1, hal 25 – 36
Saptarani, B., Aprilia, P., & Emelia, R. 2022. Tingkat Kepatuhan Penggunaan Obat Anti Tuberkulosis Pada Proses Penyembuhan Pasien Di RSUA Dr M. Salamun Bandung. Cerdika: Jurnal Ilmiah Indonesia, Vol (2) No. 2 hal 304 – 311
Saragih, H., Dereng, I., Tampubolon, L., & Sembiring, L. S. 2024. Hubungan Dukungan Keluarga Dengan Kepatuhan Pasien TBC Dalam Mengkonsumsi Obat OAT Di Rumah Sakit Santa Elisabeth Batam Kota Tahun 2022. Jurnal Cakrawala Ilmiah, Vol (3) No. 6 hal 1823 – 1832
Setiawan, M.D., Fauziah, F., Edriani, M., & Gurning, F.P. 2020. Analisis Mutu Pelayanan Kesehatan Program Jaminan Kesehatan Nasional (A: Systematic Review). Jurnal Pendidikan Tambulasi, Vol (2) No. 2, hal 12869 – 12873
Setyowati, L. dan Emil, E.S. 2021. Analisis Tingkat Kepatuhan Pengunaan Obat Tuberkulosis Mengunakan Medication Adherence Ranting Scale (MARS). JI-KES (Jurnal Ilmu Kesehatan), Vol (5) No. 1, hal 14 – 18
Siregar, I., Siangian, P., & Effendy, E. 2019. Dukungan Keluarga meningkatkan Kepatuhan Minum Obat Pada Penderita Tuberkulosis Paru Di Kabupaten Tapanuli Utara. Jurnal Kedokteran Brawijaya, Vol (30) No. 4, hal 309 – 312
Sugiyono. 2019. Metode Penelitian Kuantitatif Kualitatif dan R&D. Bandung: Alfabeta
Syaifiyatul, H., Humaidi, F., & Anggarini, D.R. 2020. Kepatuhan Minum Obat Anti Tuberkulosis Pada Pasien Tbc Regimen Kategori I Di Puskesmas Palengaan. Jurnal Ilmiah Farmasi Attamru (JIFA), Vol (1) No. 1, hal 7 – 14
Undang – Undang (UU) Nomor 36 Tahun 2009 Tetang Kesehatan 2009. (Online), (https://peraturan.bpk.go.id/Details/38778/uu-no-36-tahun-2009), diakses 6 Februari 202
Copyright (c) 2025 Jurnal Kesehatan Farmasi
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work
